On GPS Sunday: How should U.S. respond to ISIS threat? And, a path to cheap nuclear fuel?

Watch "Fareed Zakaria GPS," this Sunday at 10 a.m. and 1 p.m. ET on CNN

On GPS this Sunday: First, Fareed offers his take on the Middle East – and why one of the key tenets of U.S. foreign policy in the region has been fundamentally misguided.

Then, he convenes a panel of leading analysts including Emma Sky, former chief political adviser to the commander of U.S. forces in Iraq and author of the forthcoming book Dove Among Hawks: a Memoir of High Hopes and Missed Opportunities, Council on Foreign Relations President Richard Haass, Shadi Hamid, a fellow at the Brookings Institution's Center for Middle East Policy, and David Kilcullen, a former Australian Army officer and counter-insurgency expert who served as senior adviser to U.S. General David Petraeus during the Iraq War.

Also, if you think relations between the United States and Russia are rough right now, just wait.  Russia intends to soon have a spy station in Cuba again. What in the world?

And, a cheap nuclear power plant that uses nuclear waste as its fuel. Sound like a pipe-dream? Fareed will introduce you to someone who says that she can make it a reality.